WebThe HTRF Cereblon binding assay is a competitive assay format which uses Thalidomide-Red as Cereblon ligand, a GST tagged human Cereblon protein, and an anti GST … WebThe Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding …
HTRF Thalidomide-Red Ligand Cisbio
WebHTRF MDM2 Binding Kit - Standard can be used as a standard to check assay reproducibility and as a competitor compound to determine the non specific binding of MI-1061 Red Ligand in binding assays. Benefits PRODUCED BY MANUFACTURER STRINGENT QUALITY CONTROL Can we help you? Have any question? Web• HTRF Cereblon binding kit • HTRF PPI reagents ... Anti-human IgG4 AL142 Anti-Maltose-Binding Protein (MBP) AL134 Anti-mouse IgG AS104 AL105 Anti-Protein C tag AL172 Anti-rabbit IgG AS105 AL104 Anti-rat IgG AS110 AL106 Anti-sheep IgG AL132 Anti-V5 AL129 Glutathione (GSH) 6765300/1/2/3 AL109 st chris vacancies
HTRF HUMAN CEREBLON BINDING KITS - PerkinElmer
Web28 nov. 2013 · Lenalidomide also promoted the binding of cereblon to exogenous IKZF1 (fig. S16) and to endogenous IKZF1 and IKZF3 (fig. S17) when added directly to binding assays performed with cell extracts. Moreover, wild-type cereblon, but not the YWAA variant, promoted the ubiquitylation of IKZF1 in vivo ( Fig. 3C ) and in vitro ( Fig. 3D ) … WebAssessment of MT802 binding toward Cereblon with AlphaLISA®️ and HTRF®️ Cereblon binding assay – (PROTAC: MT802; E3 ligand : Pomalidomide) Is a Ternary complex formed ? Inside the cell, a PROTAC engages with either the specific E3 ligase or the target protein to form the corresponding binary complex , followed by the involvement … WebAssay principle. The HTRF XIAP BIR3 Binding Kit is a competitive assay format which uses XIAP BIR3 Red Ligand (based on A410099.1 derivative), a GST tagged human XIAP BIR3 binding domain, and an anti GST Terbium Cryptate-labeled antibody. XIAP binding compounds compete with the Red Ligand and thereby prevent FRET from occurring. st chris vandalia mass times