Irf3 compound name
WebEnzymatic interactions of IRF3 We report here that the IkappaB kinase (IKK)-related kinases IKKepsilon and TANK-binding kinase 1 are components of the virus-activated kinase that … WebQing Yang, Hong-Bing Shu, in Advances in Immunology, 2024. 2.4.5 Regulation of IRF3 activity. Upon viral infection, IRF3 undergoes phosphorylation at S396 by TBK1, and …
Irf3 compound name
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WebMar 10, 2011 · IRF8 cooperates with IRF3 to regulate IFN-β transcription. (A) The genomic sequence of human IFN-β from −79 bp to −58 bp. The IRF3- and IRF8-binding sites are labeled in blue and red, respectively. (B) THP-1 cells were induced with LPS for 2 hours before total lysates were harvested and immunoprecipitation was performed. WebIrf3 - interferon regulatory factor 3 Mus musculus Synonyms: C920001K05Rik, IRF-3, Interferon regulatory factor 3 , Bibeau-Poirier, A. , , Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text.
IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association … See more Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor. See more IRF3 has been shown to interact with IRF7. See more • Pitha PM, Au WC, Lowther W, Juang YT, Schafer SL, Burysek L, Hiscott J, Moore PA (1999). "Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth" See more • Interferon+Regulatory+Factor-3 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • FactorBook IRF3 See more WebIdentification and Characterization of Small-Molecule IRF3-Dependent Immune Activators for Pharmaceutical Development . Authors Marie H Foss 1 , Susan L Stevens 1 , Haihong Jin 2 , Elyse M Allen 3 , Dylan Nelson 4 , Victor DeFilippis 5 , Aaron Nilsen 2 , Mary P Stenzel-Poore 3 Affiliations 1 Neuralexo, Inc., Portland, Oregon 97239, United States.
WebWe sought to develop a small-molecule activator of interferon regulatory factor 3 (IRF3), an essential innate immune transcription factor, which could potentially be used … WebIdentification and Characterization of Small-Molecule IRF3-Dependent Immune Activators for Pharmaceutical Development . Authors Marie H Foss 1 , Susan L Stevens 1 , Haihong …
WebDec 6, 2010 · IRF3-CL shares a common N-terminus with IRF3 and contains a partial IAD, but has a unique C-terminus (328–452 aa). aa, amino acids; AIE, autoinhibition element; DBD, …
WebA: The compound given is Na2CrO4·5H2O. Q: What is the correct IUPAC name for P4S3? A: The IUPAC nomenclature is defined as the method that involves the naming of the organic compound… Q: What is the IUPAC name of C4H8? Provide brief explanation. A: It is a hydrocarbon and follow formula CnH2n+2 which is general formula for alkane intrinsic data typesWebMar 21, 2024 · IRF3 (Interferon Regulatory Factor 3) is a Protein Coding gene. Diseases associated with IRF3 include Encephalopathy, Acute, Infection-Induced 7 and … new mexico tech clubsWebIRF3 is a member of the interferon regulatory transcription factor (IRF) family. [5] IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory ... intrinsic cutoff frequencyWebIrF3 molecular weight Molar mass of IrF3 = 249.2122096 g/mol This compound is also known as Iridium (III) Fluoride. Convert grams IrF3 to moles or moles IrF3 to grams … new mexico tech cost of attendanceWebIrF3 Elemental composition of IrF3 Element Symbol Atomic weight Atoms Mass percent Iridium Ir 192.217 1 77.1298 Fluorine F 18.9984032 3 22.8702 Mass percent composition … new mexico tech alumni listWebThe IRF3 homodimer or IRF3/7 heterodimer binds to CREBBP which, as we have discussed in Chapter 7, “Bringing the Signal into the Nucleus,” is an essential co-activator for gene transcription. Transcriptional activity of IFR3 requires the cooperation of NFKB (return to Figure 13-5). All this leads to enhanced expression of the interferon-β ... intrinsic curlyWebJun 1, 2024 · One of the major PRRs leading to IRF3 activation is toll-like receptor 3 (TLR3), which is a critical receptor for viral double stranded RNA. The binding of TLR3 to its ligand … intrinsic curly me